Formulation of the rabies viral glycoprotein containing a positively charged tail used for association with nucleic acids. This protein enables the selective delivery of the nucleic acid into neuronal cells.
This peptide is a 29 amino acid fragment derived from rabies virus glycoprotein (RVG). Because neurotropic viruses cross the blood-brain barrier to infect brain cells, the same strategy may be used to enter the central nervous system and deliver siRNA to the brain. This peptide specifically binds to the acetylcholine receptor expressed by neuronal cells.
• NeuroTarget Transfection Agent
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